Laboratory On-Line Analyzers Training

Introduction

The growth of modern technology has confronted the analytical chemist with a host of new and increasingly complex materials and has posed more stringent demands for greater sensitivity, reliability, and speed. On the other hand, developments in instrumentation have provided the analyst with new techniques, instruments, procedures, and reagents for dealing with these problems. This very expansion of equipment, reagents, and methodology has, however greatly complicated the task of the chemist searching for the best way of attacking a new or unfamiliar sample. This workshop is intended to provide analytical chemists and their colleagues in related sciences with concise and convenient summaries of the fundamental data and the practical procedures that are most important and useful among the instrumental methods in analytical chemistry.

In modern laboratories, there is an increasing need for analysts to understand and be able to quantify the performance of analytical instruments, in particular with respect to the following:

• Specifying equipment for purchase
• Estimating uncertainties in instrumental measurements
• Quantifying and demonstrating performance quality

This workshop links together with an understanding of performance characteristics with an appreciation of the limitations imposed by instrument design, leading to the interplay of the validation and qualification processes within quality assurance systems. This workshop includes a unique framework of topics covers the major instrumental techniques of spectrophotometry, chromatography, capillary electrophoresis, and atomic emission spectroscopy. The use of case studies, exercises, and practical applications will help participants to develop a thorough understanding of the various concepts that underpin the different techniques.

Analytical Chemistry is concerned with providing qualitative and quantitative information about the chemical and structural composition of a sample of matter. A huge variety of samples, from high concentrations of elements in alloy steels to part-per-billion levels of drugs in biological tissue, are handled by the analyst. The field is founded on the conversion of a measured physical property of the species being examined to a usable signal. It is generally divided into two categories, classical and instrumental, on the basis of its historical development. The overall strategy is to prepare a sample correctly, choose a particular method of analysis, and report the results in a meaningful format, which may include a statistical evaluation.

This course takes you from the foundations of analytical science to state-of-the-art techniques and instrumentation. The course covers general analytical chemistry and instrumental analysis. Carefully chosen worked examples show you how analytical problems can effectively be solved and how calculations should be performed. Study questions and recommended reading for further study are provided within the course. 

Objectives

Upon the successful completion of this workshop, participants will be able to:-

• Understand the various techniques of Analytical Measurements
• Calculate Uncertainty and Random Error
• Aware of the Instrument Performance Characteristics which include types and interaction between different characteristics.
• Prepare and handle Sample for different Analytical Instrumentations
• Extract Analyses from complex matrices
• Understand, use, maintain and troubleshoot Inductively Coupled Plasma - Optical Emission Spectroscopy
• Understand, use, maintain and troubleshoot Ultraviolet, Visible Spectrophotometers
• Understand, use, maintain and troubleshoot Infrared and Raman Spectroscopy
• Increase understanding with the operational & performance qualification of data validation and be able to improve maintenance, calibration & performance testing
• Determine the operational qualification of software and computer systems including its implementation & documentation
• Learn the validation of analytical methods including quality control plan, revalidation and the parameters & strategies for method validation
• Understand data validation and evaluation of uncertainty and be able to employ the measurement & reporting of uncertainty
• Identify the requirements, guidelines & application of certified reference standards used in data validation for analytical laboratories and be able to learn the process of preparation, testing & the correct use of certified reference materials
• Recognize the qualification, roles & responsibilities of the recruiting people for data validation and be able to conduct training for enhancement & development
• Explain how to conduct proficiency testing for external laboratory qualification and identify who should participate in proficiency testing
• Develop in-depth knowledge on the process of planning & implementing inspections & audits and be able to prepare an audit report & checklist 
• Understand, use, maintain and troubleshoot Capillary Electrophoresis
• Understand, use, maintain and troubleshoot Electrolytic Conductance and pH
• Understand, use, maintain and troubleshoot Gas Chromatography
• Acquire insight and skills in general qualitative and quantitative analytical chemistry
• Teach basic analytical principles and training preparation to instrumental, electrochemical, spectroscopic and separationally-oriented analysis.
• Know the concept of visual spectrometry and become aware with its qualitative and quantitative analysis
• Determine the practical application of atomic absorption spectrometry
• Develop in-depth knowledge about electro-chemical analysis and differentiate absolute conductivity from cation conductivity
• Understand the principle of analytical reaction chemistry by discussing the theory of titrimetry & gravimetry, identifying buffers, describing visual & electro-mechanical indication and identifying the other types of titrations
• Become familiar with the theory of gas chromatography including colums and detectors and identify the effect of temperature and flow on analysis
• Describe special water chemistry  which includes total carbon, total organic & inorganic carbon & ion chromatography and recognize its importance in analytical chemistry & process analyzers
• Understand Instrument and Method Validation 

Training Methodology

This is an interactive course. There will be open question and answer sessions, regular group exercises and activities, videos, case studies, and presentations on best practice. Participants will have the opportunity to share with the facilitator and other participants on what works well and not so well for them, as well as work on issues from their own organizations. The online course is conducted online using MS-Teams/ClickMeeting.

Who Should Attend?

This workshop is intended for all chemical laboratory professionals, Laboratory Managers, Superintendents, Supervisors, Engineers, Chemists, Analysts and Technicians. Laboratory Managers, Supervisors, Chemists, Analysts and Technicians. Further, the course is a must for Instrumentation personnel who are dealing with laboratory equipment and online process instruments and analyzers.

Course Outline

The program will cover an assortment of topics in Analytical Chemistry, including:

• Separation Methods (CE, LC, GC and others)
• Mass Spectrometry
•  Nanosciences in Analytical Chemistry
• Bioanalytical Methods
• Analytical Spectroscopy and Electrochemistry
• Proteomics, Genomics and Metabolomics
• Water Analytical Chemistry
• Analytical Chemistry in Homeland Security
• Forensic Analytical Chemistry
• Sensors
• Chemometry
• Computerized Analytical Chemistry
• Legal aspects of Analytical Chemistry
• Regulatory and Metrology
• Education of Analytical Chemistry